Etude par spectrophotométrie UV-visible de l’interaction des extraits de Gymnanthemum amygdalinum (Delile) sch. Bip. Exwalp (Asteraceae) avec le glucose oxydase et le radical DPPH° in vitro.

Abstract

Diabetes mellitus is a metabolic disease characterized by chronic hyperglycemia resulting from defects in insulin secretion or action, leading to various organ complications. It is diagnosed by elevated blood glucose levels and is classified into two types: type I diabetes, which requires insulin administration, and type II diabetes, often associated with environmental and genetic factors. The global prevalence of diabetes is rapidly increasing, with alarming projections for the year 2050. In addition to conventional treatments, the use of medicinal plants appears to be a promising alternative. Tests have revealed the presence of several bioactive compounds, including tannins, flavonoids, and polyphenols. Antioxidant activity depends on the concentration of the extracts, while the organic extract demonstrates a better interaction with glucose in vitro than the aqueous extract. These results open new perspectives for the development of natural treatments against diabetes and highlight the need for further research.